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N6283 Sigma

Natural Products Isolation

  •  ISBN-10 0-89603-362-7

  •  ISBN-13 978-0-89603-362-7



publication info   J.P. Cannell, ed., Humana Press, 1998, 480 pp., hard cover
mfr. no.   Humana


Features and Benefits

Researchers from both industry and academia present in detail, techniques for the extraction and isolation of natural products of all classes. These experienced experimentalists describe a wide array of methodologies, including basic chromatography, ion-exchange methods, HPLC, countercurrent and planar chromatography, SFE, and crystallization. For the less-experienced they offer hands-on advice − using real examples − about how to approach an extraction in general, when and why to apply a particular technique, how to carry out the methods described, and how to modify conditions according to the compound being isolated.

Table of Contents

How to Approach the Isolation of a Natural Product, Initial Extraction and Product Capture, Supercritical Fluid Methods, Isolation by Low-Pressure Column Chromatography, Isolation by Ion-Exchange Methods, Isolation by Preparative HPLC, Isolation by Planar Chromatography, Separation by High-Speed Countercurrent Chromatography, Crystallization and Final Stages of Purification, Dereplication and Partial Identification of Natural Products, Purification of Water-Soluble Natural Products, Special Problems with the Extraction of Plants, Isolation of Marine Natural Products, Scale-Up of Natural Products Isolation, Follow-Up of Natural Product Isolation,

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