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N6505 Sigma

β-Nicotinamide adenine dinucleotide 2′-phosphate reduced tetrasodium salt hydrate

≥95% (HPLC)

Synonym: β-NADPH, 2′-NADPH hydrate, Coenzyme II reduced tetrasodium salt, Dihydronicotinamide adenine dinucleotide phosphate tetrasodium salt, NADPH Na4, TPNH2 Na4, Triphosphopyridine nucleotide reduced tetrasodium salt



Related Categories Biochemicals and Reagents, Cofactors, Core Bioreagents, Enzymes, Inhibitors, and Substrates, Nucleosides and Nucleotides,
assay   ≥95% (HPLC)
  ≥95% (spectrophotometric assay)
storage temp.   −20°C


Biochem/physiol Actions

Electron donor; cofactor for many redox enzymes including nitric oxide synthetase

Other Notes

Packaged based on solid weight.


1 g in poly bottle

25, 100, 250, 500 mg in poly bottle

Preparation Note

Enzymatically reduced.


β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP).

Price and Availability

Suggested Laboratory Gloves

Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.

Safety & Documentation

Safety Information

WGK Germany 

Protocols & Articles

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06693 Timestrip Plus -20 °C

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