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N7756 Sigma

N-Nitrosodimethylamine

Synonym: Dimethylnitrosamine

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Properties

vapor pressure   5 mmHg ( 20 °C)
description   Bulk package
InChI Key   UMFJAHHVKNCGLG-UHFFFAOYSA-N
refractive index   n20/D 1.437(lit.)
bp   153 °C/774 mmHg(lit.)
density   1.01 g/mL(lit.)
storage temp.   2-8°C

Description

Biochem/physiol Actions

Induces gastric, liver, kidney and lung cancer in mice and rats.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN3382 - class 6.1 - PG 1 - EHS - Toxic by inhalation liquid, n.o.s., HI: all (not BR)
WGK Germany 
3
RTECS 
IQ0525000
Flash Point(F) 
141.8 °F
Flash Point(C) 
61 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
Vicki Caligur
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Biofiles, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Events, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Sequences, Transcription, Type, transformation

DNA Damage and Repair

Damage to cellular DNA is involved in mutagenesis and the development of cancer. The DNA in a human cell undergoes several thousand to a million damaging events per day, generated by both external (e...
Keywords: AGE, Alkylations, Apoptosis, Biochemistry, Cancer, Carcinogens, Catalysis, Clinical, DNA replication, Deaminations, Degradations, Eliminations, Environmental, Enzymology, Gene expression, Genetic, Infrared spectroscopy, Metabolites, Methylations, Mutagens, Oncology, Oxidations, Polymorphisms, Rearrangements, Recombination, Substitutions, Transcription, transformation

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Peer-Reviewed Papers
15

References

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