N8000 Sigma

1-Naphthyl butyrate

esterase substrate

Synonym: Butanoic acid 1-naphthyl ester, Butyric acid 1-naphthyl ester



Related Categories Biochemicals and Reagents, Chromogen, Enzyme Substrate, Enzyme Substrates, Enzymes, Inhibitors, and Substrates,
description   esterase substrate
refractive index   n20/D 1.571(lit.)
bp   125-130 °C/1 mmHg(lit.)
density   1.091 g/mL at 20 °C(lit.)
storage temp.   −20°C



1, 5, 10 g in serum bottle

250 mg in serum bottle


Esterase substrate.

Price and Availability

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Safety & Documentation

Safety Information

NA 1993 / PGIII
WGK Germany 
Flash Point(F) 
143.6 °F
Flash Point(C) 
62 °C

Protocols & Articles

Peer-Reviewed Papers


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High affinity binding of albicidin phytotoxins by the AlbA protein from Klebsiella oxytoca. Zhang L, Xu J, and Birch RG Microbiology 144 ( Pt 2), 555-9, (1998)


Ultrastructural cytochemistry of non-specific esterase in murine peritoneal macrophages. Rademakers LH, Van Blokland WT, De Frankrijker JF, et al. Histochem. J. 21(5), 301-8, (1989)


Chromosome pattern in childhood acute nonlymphocytic leukemia (ANLL). Kaneko Y, Rowley JD, Maurer HS, et al. Blood 60(2), 389-99, (1982)


Cytochemical demonstrations of protease in human peripheral blood cells by use of new alpha-naphthyl ester substrates. Honda T, Hitomi Y, Niinobe M, et al. Histochemistry 77(3), 299-302, (1983)


Recommended methods for cytological procedures in haematology. International Committee for Standardization in Haematology (ICSH). Shibata A, Bennett JM, Castoldi GL, et al. Clin. Lab. Haematol. 7(1), 55-74, (1985)


Carboxylesterase activity, cDNA sequence, and gene expression in malathion susceptible and resistant strains of the cotton aphid, Aphis gossypii. Pan Y, Guo H, and Gao X Comp. Biochem. Physiol. B Biochem. Mol. Biol. 152(3), 266-70, (2009)


A rapid spectrophotometric method for the determination of esterase activity. Miller RB and Karn RC J. Biochem. Biophys. Methods 3(6), 345-54, (1980)


alpha-Naphthyl butyrate carboxylesterase activity in human and rat nasal tissue. Mattes PM and Mattes WB Toxicol. Appl. Pharmacol. 114(1), 71-6, (1992)


Simultaneous demonstration of nonspecific esterase and chloroacetate esterase in human blood cells. Lam KW, Li CY, and Yam LT Stain Technol. 60(3), 169-72, (1985)


Nonspecific esterase of B lymphocytes from a case of chronic lymhocytic leukemia and of normal T lymphocytes: similar constellations of isoenzymes. Yourno J, Burkart P, Mastropaolo W, et al. Blood 60(1), 24-9, (1982)


Esterase isoenzymes and insecticide resistance in Frankliniella occidentalis populations from the south-east region of Spain. López-Soler N, Cervera A, Moores GD, et al. Pest Manag. Sci. 64(12), 1258-66, (2008)


Inhibition of esterase activity and an undercounting of circulating monocytes in a population of production workers. Levine MS, Fox NL, Thompson B, et al. J. Occup. Med. 28(3), 207-11, (1986)


Single incubation double esterase cytochemical reaction using a single coupling reagent. Swirsky DM J. Clin. Pathol. 37(10), 1187-90, (1984)


Monocyte nonspecific esterase. Enzymologic characterization of a neutral serine esterase associated with myeloid cells. Yourno J, Burkart P, Mastropaolo W, et al. J. Histochem. Cytochem. 34(6), 727-33, (1986)


Alpha-naphthyl-butyrate-esterase stain by Hemalog D reagents. Milanesi B Haematologica 69(3), 377-8, (1984)


Beil. 6,IV,4217

Aldrich MSDS 1, 1341:D / Corp MSDS 1 (2), 2512:B / FT-IR 2 (2), 2894:B / FT-NMR 1 (2), 1299:B / RegBook 1 (2), 1933:E / Sigma FT-IR 1 (1), 1428:D / Structure Index 1, 311:A:2 / Vapor Phase 3, 1385:A

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