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N8403 Sigma

6-Nitroso-1,2-benzopyrone

ADP-ribosyltransferase inhibitor

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Properties

Related Categories A to C, ADP ribosyltransferase, Biochemicals and Reagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme,
InChI Key   HXTDAUGEZTYMGP-UHFFFAOYSA-N
storage temp.   −20°C

Description

Application

Binds to the DNA-recognizing domain of ADP-ribosyltransferase and preferentially destabilizes one of the two zinc finger polypeptide complexes. The affected enzyme loses almost all activity, but still binds to DNA.

Binds to the DNA-recognizing domain of ADP-ribosyltransferase and preferentially destabilizes one of the two zinc finger polypeptide complexes. The affected enzyme loses almost all activity, but still binds to DNA.>

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

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LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


Biomedical Applications
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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