|Related Categories||Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates M-O, Disaccharide More...|
|sweetness||1500 × sucrose|
Flavonoid sweetening agent with potent antioxidant activity.2
Neohesperidin dihydrochalcone is an artificial sweetener. 3
Neohesperidin dihydrochalcone has been used in a study to assess levels of nine high-intensity sweeteners in various foods. 1 It can be used as a therapeutic agent on reactive oxygen species-related inflammatory disease. 2
1. Determination of nine high-intensity sweeteners in various foods by high-performance liquid chromatography with mass spectrometric detection Zygler, A., et al. Anal. Bioanal. Chem 400, 2159-72, (2011)
2. Antioxidant properties of neohesperidin dihydrochalcone: inhibition of hypochlorous acid-induced DNA strand breakage, protein degradation, and cell death. Choi, J.M. et al. Biol. Pharm. Bull. 30, 324-330, (2007)
Neohesperidin dihydrochalcone: presentation of a small molecule activator of mammalian alpha-amylase as an allosteric effector. Kashani-Amin E, Larijani B, and Ebrahim-Habibi A FEBS Lett. 587(6), 652-8, (2013)
Metabolic engineering of plant cells for biotransformation of hesperedin into neohesperidin, a substrate for production of the low-calorie sweetener and flavor enhancer NHDC. Frydman A, Weisshaus O, Huhman DV, et al. J. Agric. Food Chem. 53(25), 9708-12, (2005)
Crystal architecture and conformational properties of the inclusion complex, neohesperidin dihydrochalcone-cyclomaltoheptaose (beta-cyclodextrin), by X-ray diffraction. Malpezzi L, Fronza G, Fuganti C, et al. Carbohydr. Res. 339(12), 2117-25, (2004)
An estimation of the detection and quantitation limits of neohesperidine DC by high-performance liquid chromatography. Montijano H, Cano J, López-Cremades FJ, et al. World Rev. Nutr. Diet. 85, 125-8, (1999)
Validated high-performance liquid chromatographic method for quantitation of neohesperidine dihydrochalcone in foodstuffs. Montijano H, Borrego F, Canales I, et al. J. Chromatogr. A 758(1), 163-6, (1997)
Some sweet and bitter tastants stimulate inhibitory pathway of adenylyl cyclase via melatonin and alpha 2-adrenergic receptors in Xenopus laevis melanophores. Zubare-Samuelov M, Peri I, Tal M, et al. Am. J. Physiol. Cell Physiol. 285(5), C1255-62, (2003)
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