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N9879 Sigma

NADase from porcine brain

≥0.007 unit/mg solid

Synonym: DPN Nucleosidase, NAD+ glycohydrolase

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Description

General description

NADase is a glycohydrolase that catalyzes ADP-ribose transfer.

Packaging

5 g in poly bottle

Unit Definition

One unit will hydrolyze 1.0 μmole of β-NAD to nicotinamide and ADP-ribose per min at pH 7.3 at 37 °C.

Physical form

Acetone-dried powder

Application

NADase from porcine brain has been used in a study to investigate histidine and related compounds resulting from catalyzed ADP-riboslyation. It has also been used in a study to investigate the preparation of arylazide-substituted pyridine adenine dinucleotides for photoaffinity labeling.

Biochem/physiol Actions

Nicotinamide has been shown to inhibit NADase activity.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Related Content

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Keywords: Cell signaling, Diagnostic, Drug discovery, Molecular biology

Peer-Reviewed Papers
15

References

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