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O003 Sigma

β-Funaltrexamine hydrochloride

solid

Synonym: β-FNA hydrochloride, (E)-4-[[(5α,6β)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydroxymorphinan-6-yl]amino]-4-oxo-2-butenoic acid methyl ester hydrochloride

  • CAS Number 72786-10-8

  • Empirical Formula (Hill Notation) C25H30N2O6 · HCl

  • Molecular Weight 490.98

  •  MDL number MFCD10565941

  •  PubChem Substance ID 24897921

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   BIPHUOBUKMPSQR-NQGXHZAGSA-N
form   solid
color   white
solubility   H2O: soluble7.5 mg/mL (aqueous solutions should be promptly used)
  methanol: soluble7.6 mg/mL (do not store in ethanolic solution; methanolic solutions may be stored for several weeks at 4 °C)
storage temp.   −20°C

Description

Biochem/physiol Actions

Selective irreversible μ opioid receptor antagonist that is also a κ opioid receptor agonist.

Features and Benefits

This compound is featured on the Opioid Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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