Ouabagenin exerts cardiotonic effects through inhibition of Na+/K+-ATPase like the glycosides, albeit at significantly lower potency.1
The aglycone of the cardiac glycoside ouabain.
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Chronic hypertension induced by ouabain but not digoxin in the rat: antihypertensive effect of digoxin and digitoxin. Manunta P, Hamilton J, Rogowski AC, et al. Hypertens. Res. 23 Suppl, S77-85, (2000)
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