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O4511 Sigma

Okadaic acid from Prorocentrum concavum

≥90% (HPLC), translucent film

Synonym: OA

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme,
InChI Key   QNDVLZJODHBUFM-WFXQOWMNSA-N
assay   ≥90% (HPLC)
form   translucent film
solubility   DMSO: ≥1 mg/mL
  ethanol: ≥1 mg/mL
  methanol: ≥1 mg/mL
  H2O: insoluble
storage temp.   −20°C

Description

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.

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All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
RIDADR 
UN 3462 6.1 / PGIII
WGK Germany 
3
RTECS 
AA8227800
Protocols & Articles
Peer-Reviewed Papers
15

References

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06693 Timestrip Plus -20 °C

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