|Related Categories||Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antibiotics by Application,|
Antibiotic produced by Streptomyces rimosus.
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit.
Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Mode of Resistance: Active efflux, ribosome protection, tetracycline inactivation.
Plasma matrix metalloproteinase activity in horses after intravenous infusion of lipopolysaccharide and treatment with matrix metalloproteinase inhibitors. Fugler LA, Eades SC, Moore RM, et al. Am. J. Vet. Res. 74(3), 473-80, (2013)
Changes in the nitrogen removal performance and the properties of granular sludge in an Anammox system under oxytetracycline (OTC) stress. Yang GF, Zhang QQ, and Jin RC Bioresour. Technol. 129, 65-71, (2013)
Age-dependent effects of systemic administration of oxytetracycline on the viscoelastic properties of rat tail tendons as a mechanistic basis for pharmacological treatment of flexural limb deformities in foals. Wintz LR, Lavagnino M, Gardner KL, et al. Am. J. Vet. Res. 73(12), 1951-6, (2012)
Evaluation of antimicrobial activity against Mycoplasma mycoides subsp. mycoides Small Colony using an in vitro dynamic dilution pharmacokinetic/pharmacodynamic model. Mitchell JD, McKellar QA, and McKeever DJ J. Med. Microbiol. 62(Pt 1), 56-61, (2013)
The effect of respiratory disease and a preventative antibiotic treatment on growth, survival, age at first calving, and milk production of dairy heifers. Stanton AL, Kelton DF, LeBlanc SJ, et al. J. Dairy Sci. 95(9), 4950-60, (2012)
Development and validation of a reversed phase liquid chromatographic method for analysis of oxytetracycline and related impurities. Kahsay G, Shraim F, Villatte P, et al. J. Pharm. Biomed. Anal. 75, 199-206, (2013)
Development and validation of a liquid chromatographic/ tandem mass spectrometric method for determination of chlortetracycline, oxytetracycline, tetracycline, and doxycycline in animal feeds. Guo L, Chen Y, Zhang L, et al. J. AOAC Int. 95(4), 1010-5, (2012)
Pharmacodynamics of antimicrobials against Mycoplasma mycoides mycoides small colony, the causative agent of contagious bovine pleuropneumonia. Mitchell JD, McKellar QA, and McKeever DJ PLoS ONE 7(8), e44158, (2012)
Synergistic interactions of epigallocatechin gallate and oxytetracycline against various drug resistant Staphylococcus aureus strains in vitro. Novy P, Rondevaldova J, Kourimska L, et al. Phytomedicine 20(5), 432-5, (2013)
The interaction of polysaccharide from Auricularia polytricha with quantum dots and the protection of plasmid DNA from damage. Wang W, Zhang G, and Zou J Appl. Biochem. Biotechnol. 169(8), 2263-72, (2013)
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