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O6262 Sigma

Orexin B rat, mouse

≥97% (HPLC)

Synonym: Hypocretin 2

  • Empirical Formula (Hill Notation) C126H215N45O34S

  • Molecular Weight 2936.40

  •  MDL number MFCD01635376

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Description

Amino Acid Sequence

Arg-Pro-Gly-Pro-Pro-Gly-Leu-Gln-Gly-Arg-Leu-Gln-Arg-Leu-Leu-Gln-Ala-Asn-Gly-Asn-His-Ala-Ala-Gly-Ile-Leu-Thr-Met-NH2

Packaging

0.1, 0.5 mg in serum bottle

Biochem/physiol Actions

Orexins (hypocretins) comprise a family of hypothalamic peptides that are involved in the initiation of sleep and in feeding behavior. Orexin A stimulates food intake through activation of the OX1 receptor. Orexin B activates OX2 receptors. Both OX1 and OX2 receptors are involved in maintaining arousal. OX2 receptors appear to be inhibitory autoreceptors on orexin-containing neurons.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
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