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O9262 Sigma

1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphorylcholine

≥99% (TLC), waxy solid

Synonym: ET-18-OCH3

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   MHFRGQHAERHWKZ-HHHXNRCGSA-N
assay   ≥99% (TLC)
form   waxy solid
color   white
solubility   ethanol: soluble15 mg/mL at 45 °C
  chloroform: soluble >25 mg/mL
  DMSO: soluble
shipped in   wet ice
storage temp.   −20°C

Description

Biochem/physiol Actions

Phosphoinositide-specific phospholipase C (PI-PLC) inhibitor.

Preparation Note

1-O-Octadecyl-2-O-methyl-sn-glycero-3- phosphorylcholine is soluble in ethanol at 15 mg/ml and in chloroform at 25 mg/ml.
The following steps are for the preparation of a DMSO stock solution.
1. Solubilize 1-O-Octadecyl-2-O-methyl-sn-glycero-3-phosphorylcholine in chloroform.
2. Deposit a thin film of the compound on the sides of a container by evaporating the chloroform with a stream of nitrogen or argon.
3. Add DMSO and vortex mix to dissolve the compound from the sides of the container. The DMSO or ethanol solutions may be diluted at least 1000-fold directly into stirred aqueous cell culture medium.

Features and Benefits

This compound is featured on the Phospholipase C page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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