• USA Home
  • O9381 - Okadaic acid from Prorocentrum concavum

EMAIL THIS PAGE TO A FRIEND
O9381 Sigma

Okadaic acid from Prorocentrum concavum

92-100% (HPLC)

Synonym: OA

Purchase

Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Kinase/Phosphatase Biology,
InChI Key   QNDVLZJODHBUFM-WFXQOWMNSA-N
assay   92-100% (HPLC)
solubility   DMSO: ≥1 mg/mL
  ethanol: ≥1 mg/mL
  methanol: ≥1 mg/mL
  H2O: insoluble
shipped in   dry ice
storage temp.   −20°C

Description

Preparation Note

Isolated from unialgal cultures of dinoflagellates.

Biochem/physiol Actions

Dinoflagellate toxin and an ionophore-like polyether derivative of a 38 carbon, fatty acid. Readily enters cells. Inhibitor of type 1 and type 2A protein phosphatases. Does not inhibit tyrosine phosphatases, alkaline phosphatases or acid phosphatase. Known tumor promotor. Used to study various cellular processes including cell cycle, apoptosis, nitric oxide metabolism and calcium signaling.

Features and Benefits

This compound is featured on the Phosphoprotein Phosphatases (Serine/Threonine) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
RIDADR 
UN 3462 6.1 / PGIII
WGK Germany 
3
RTECS 
AA8227800

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?