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P0048 Sigma

Pemoline

≥98% (HPLC)

Synonym: 2-Amino-5-phenyl4(5H)-oxazolone, Phenylisohydantoin

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Properties

Related Categories Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Boehringer Ingelheim, Cell Biology,
InChI Key   NRNCYVBFPDDJNE-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   solid
drug control   USDEA Schedule IV; Home Office Schedule 4.2; psychotrope; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada; psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
solubility   DMSO: soluble28 mg/mL
originator   Boehringer Ingelheim
storage temp.   2-8°C

Description

Biochem/physiol Actions

Pemoline is a CNS stimulant. Pemoline is used to treat attention-deficit hyperactivity disorder (ADHD). Pemoline is a Schedule IV drug and offers some advantages over other stimulants in that it does not reduce the appetite or cause dry mouth.

Features and Benefits

This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Boehringer Ingelheim. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
RQ2975000

Documents

Certificate of Analysis

Protocols & Articles

Articles

Dopamine Receptors

Dopamine receptors were initially differentiated into two major types based on the ability of dopamine to stimulate (D1) or inhibit (D2) adenylyl cyclase activity and produce the second-messenger mol...
Keywords: Atomic absorption spectroscopy, Dopamine agents, Gene expression, Genetic, Genetics, Ligands, Methylations, Parkinson Disease, Schizophrenia, Transduction

Peer-Reviewed Papers
15

References

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