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P0057 Sigma

PPBP maleate

≥98% (HPLC), powder

Synonym: 4-phenyl-1-(4-phenylbutyl)-piperidine maleate, 4-PPBP maleate

  • CAS Number 207572-62-1

  • Empirical Formula (Hill Notation) C21H27N · xC4H4O4

  • Molecular Weight 293.45 (free base basis)

  •  MDL number MFCD00209909

  •  PubChem Substance ID 329820001

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, PI-PZ
InChI Key   OASPNIMFGJVLES-BTJKTKAUSA-N
assay   ≥98% (HPLC)
form   powder
storage condition   desiccated
color   off-white
solubility   DMSO: >20 mg/mL
storage temp.   2-8°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

PPBP maleate is a potent σ1 receptor ligand. PPBP is a very potent agonist of σ1 receptor (Ki = 0.8 nM).

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Articles

Sigma Receptors

Although they have undergone a substantial transformation from the time they were first proposed in the mid-1970s, a unifying picture appears to be emerging for sigma receptors. Current interest is r...
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