|Related Categories||Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Corticosteroid, Cytokines, Growth Factors and Hormones,|
100, 250 mg in poly bottle
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Development of humanized steroid and xenobiotic receptor mouse by homologous knock-in of the human steroid and xenobiotic receptor ligand binding domain sequence. Igarashi K, Kitajima S, Aisaki K, et al. J. Toxicol. Sci. 37(2), 373-80, (2012)
The nuclear receptors constitutive active/androstane receptor and pregnane x receptor activate the Cyp2c55 gene in mouse liver. Konno Y, Kamino H, Moore R, et al. Drug Metab. Dispos. 38(7), 1177-82, (2010)
Possible protective role of pregnenolone-16 alpha-carbonitrile in lithocholic acid-induced hepatotoxicity through enhanced hepatic lipogenesis. Miyata M, Nomoto M, Sotodate F, et al. Eur. J. Pharmacol. 636(1-3), 145-54, (2010)
Assessment of cytochrome P450 fluorometric substrates with rainbow trout and killifish exposed to dexamethasone, pregnenolone-16alpha-carbonitrile, rifampicin, and beta-naphthoflavone. Smith EM, Wilson JY. Aquat. Toxicol. 97, 324-333, (2010)
Effects of pregnenolone-16alpha-carbonitrile on vitamin E status and protein levels of antioxidant enzymes in male rats fed a vitamin E-supplemented diet. Shaw HM and Chen WH Redox Rep. 14(2), 61-8, (2009)
A PXR-mediated negative feedback loop attenuates the expression of CYP3A in response to the PXR agonist pregnenalone-16α-carbonitrile. Bailey I, Gibson GG, Plant K, et al. PLoS ONE 6(2), e16703, (2011)
Disruption of thyroid hormone homeostasis in Ugt1a-deficient Gunn rats by microsomal enzyme inducers is not due to enhanced thyroxine glucuronidation. Richardson TA and Klaassen CD Toxicol. Appl. Pharmacol. 248(1), 38-44, (2010)
Role of UDP-glucuronosyltransferase (UGT) 2B2 in metabolism of triiodothyronine: effect of microsomal enzyme inducers in Sprague Dawley and UGT2B2-deficient Fischer 344 rats. Richardson TA and Klaassen CD Toxicol. Sci. 116(2), 413-21, (2010)
Organic anion transporting polypeptide 2-mediated uptake of paclitaxel and 2'-ethylcarbonate-linked paclitaxel in freshly isolated rat hepatocytes. Tanino T, Nawa A, Nakao M, et al. J. Pharm. Pharmacol. 61(8), 1029-35, (2009)
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