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  • P0607 - Anti-Presenilin-2, N-terminal antibody produced in rabbit

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P0607 Sigma

Anti-Presenilin-2, N-terminal antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-AD3L, Anti-AD4, Anti-PS2, Anti-PSEN2, Anti-Presenilin 2 (Alzheimer 4), Anti-STM2

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Alzheimer′s Disease, Antibodies for Neurobiology, Antibodies for Neurodegenerative Diseases Research,
species reactivity   mouse, rat, human
application(s)   immunohistochemistry (frozen sections): 2 μg/mL using 4% paraformaldehyde-fixed mouse brain tissue
  western blot: 1-2 μg/mL using mouse or rat brain extracts
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
mol wt   antigen mol wt 28 kDa
shipped in   wet ice
storage temp.   2-8°C
Gene Information   human ... PSEN2(5664)
mouse ... Psen2(19165)
rat ... Psen2(81751)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to amino acids 7-24 of the N-terminal of human presenilin-2 (PS-2). The sequence is the same in mouse and rat.

Physical form

Solution in in 0.05 M sodium phosphate buffer, pH 7.5, containing 0.2% gelatin and 0.1% sodium azide.

Specificity

Detects an N-terminal proteolytic fragment. Additional bands are observed, probably corresponding to aggregated, modified, or intact PS-2.

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