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  • P0713 - Anti-Protein Kinase Cζ antibody produced in rabbit

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P0713 Sigma

Anti-Protein Kinase Cζ antibody produced in rabbit

whole antiserum

Synonym: Anti-PKC ζ

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology, PR-PR,
species reactivity   mouse, rat
application(s)   microarray: suitable
  western blot: suitable using rat brain extract and mouse NIH3T3 fibroblast cell lysate
clone   polyclonal
antibody form   whole antiserum
mol wt   antigen mol wt 78 kDa
contains   15 mM sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   mouse ... Prkcz(18762)
rat ... Prkcz(25522)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

Synthetic peptide corresponding to the C-terminal variable (V5) region (amino acids 577-592) of PKC ζ coupled to KLH.

General description

Protein Kinase C (PKC) is a 76-93 kD phospholipid-dependent enzyme that belongs to serine/threonine protein kinases family. It has a pivotal role in cell growth and differentiation, modulation of neurotransmission, signal transduction and oncogenesis. PKC ζ isoform is expressed mainly in many cells and tissues and is activated by cis- unsaturated fatty acids. Anti-protein kinase C ζ antibody can be used for studying differential tissue expression and intracellular localization of PKC ζ. It can also be used for studying PKC expression in normal and neoplastic tissues. Rabbit anti-protein kinase C ζ antibody reacts specifically with PKC ζ (78 kD) from rat brain extract. The product is also specific for PKC ζ (78-80 kD proteins appearing as doublet) from NIH 3T3 mouse fibroblasts lysate.

Application

Anti-protein kinase C ζ antibody can be used in immunoblot to detect PKC ζ isoenzyme by using rat brain extracts and cell culture extracts. It can also be used in microarray.

Price and Availability


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