|Related Categories||Adrenergics, Adrenergics - Antagonists, Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules,|
|color||white to off-white|
|solubility||0.1 M NaOH: soluble0.2 mg/mL|
45% (w/v) aq 2-hydroxypropyl-β-cyclode|
|0.1 M HCl: soluble20 mg/mL|
|Gene Information||human ... ADRB1(153), HTR1A(3350)|
β1-adrenoceptor antagonist; putative 5-HT1A serotonin receptor agonist; vasodilator.
Shelf-life of the powder is at least five years.
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. P0778.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P261-P305 + P351 + P338|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Gloves|
|Hazard Codes (Europe)||Xn|
|Risk Statements (Europe)||22-36/37/38|
|Safety Statements (Europe)||26-36|
Download BioFiles v7 n5 (3.18 Mb PDF) Back to Pharmaceutical Drugs and Drug Candidates homepage
BioFiles v7 n5, 2012, 5–20
Keywords: AGE, Antihypertensives, Cardiovascular, Clinical, Diuretics, Pharmaceutical, Reductions
Pindolol suppresses serotonergic neuronal activity and does not block the inhibition of serotonergic neurons produced by 8-hydroxy-2-(di-n-propylamino) tetralin in awake cats. Fornal, C.A., et al. J. Pharmacol. Exp. Ther. 291, 229, (1999)
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. Michael H Abraham et al Eur. J. Med. Chem. 43, 478-85, (2008)
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids. Markus Fridén et al J. Med. Chem. 52, 6233-43, (2009)
Synthesis and characterization of high-affinity 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene-labeled fluorescent ligands for human ?-adrenoceptors. Jillian G Baker et al J. Med. Chem. 54, 6874-87, (2011)
Corp MSDS 1 (2), 2840:C / FT-IR 2 (3), 3584:C / RegBook 1 (2), 2409:C / Sigma FT-IR 1 (1), 699:D / Structure Index 1, 382:B:3
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