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P0884 Sigma

(±)-Propranolol hydrochloride

≥99% (TLC), powder

Synonym: (±)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride, DL-Propranolol hydrochloride

  • CAS Number 318-98-9

  • Empirical Formula (Hill Notation) C16H21NO2 · HCl

  • Molecular Weight 295.80

  •  Beilstein Registry Number 4164259

  •  EC Number 206-268-7

  •  MDL number MFCD00012558

  •  PubChem Substance ID 24277796

Properties

Related Categories Adrenergics, Adrenergics - Antagonists, Antagonists, Approved Therapeutics/Drug Candidates, AstraZeneca,
assay   ≥99% (TLC)
form   powder
color   white
solubility   ethanol: soluble10 mg/mL
  DMSO: <14.5 mg/mL
  H2O: soluble50 mg/mL (dissolve with heat. Aqueous solutions are most stable at pH 3.0 and decompose rapidly at basic pH. Decomposition is accompanied by discoloration of the solution.)
  45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble8.0 mg/mL
storage temp.   2-8°C
Gene Information   human ... ADRB1(153), ADRB2(154), ADRB3(155), HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358)

Description

Biochem/physiol Actions

β-adrenoceptor antagonist; 5-HT1/5-HT2 serotonin receptor antagonist; cardiac depressant (anti-arrhythmic).

Caution

Shelf-life of the solid is at least four years if stored protected from the uptake of moisture.

Packaging

1 g in poly tube

5, 25, 100 g in poly bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®,1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



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