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  • P0884 - (±)-Propranolol hydrochloride


P0884 Sigma

(±)-Propranolol hydrochloride

≥99% (TLC), powder

Synonym: (±)-1-Isopropylamino-3-(1-naphthyloxy)-2-propanol hydrochloride, DL-Propranolol hydrochloride

  • CAS Number 318-98-9

  • Empirical Formula (Hill Notation) C16H21NO2 · HCl

  • Molecular Weight 295.80

  •  Beilstein Registry Number 4164259

  •  EC Number 206-268-7

  •  MDL number MFCD00012558

  •  PubChem Substance ID 24277796


Related Categories Adrenergics, Adrenergics - Antagonists, Antagonists, Approved Therapeutics/Drug Candidates, AstraZeneca,
assay   ≥99% (TLC)
form   powder
color   white
solubility   ethanol: soluble10 mg/mL
  DMSO: <14.5 mg/mL
  H2O: soluble50 mg/mL (dissolve with heat. Aqueous solutions are most stable at pH 3.0 and decompose rapidly at basic pH. Decomposition is accompanied by discoloration of the solution.)
  45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble8.0 mg/mL
storage temp.   2-8°C
Gene Information   human ... ADRB1(153), ADRB2(154), ADRB3(155), HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358)


Biochem/physiol Actions

β-adrenoceptor antagonist; 5-HT1/5-HT2 serotonin receptor antagonist; cardiac depressant (anti-arrhythmic).


Shelf-life of the solid is at least four years if stored protected from the uptake of moisture.


1 g in poly tube

5, 25, 100 g in poly bottle

Price and Availability

Suggested Laboratory Gloves

Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.

New TruPAGE™ Pre-cast Polyacrylamide Gels

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United States Pharmacopeia (USP) Reference Standard

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European Pharmacopoeia (EP) Reference Standard

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pharmaceutical secondary standard; traceable to USP and PhEur

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