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P1319 Sigma

Thyrotropin releasing hormone

≥98% (HPLC), powder

Synonym: L-Pyroglutamyl-L-histidyl-L-prolinamide, TRF, TRH, Thyroliberin, pGlu-His-Pro amide

  • CAS Number 24305-27-9

  • Empirical Formula (Hill Notation) C16H22N6O4

  • Molecular Weight 362.38

  •  Beilstein Registry Number 770238

  •  EC Number 246-143-4

  •  MDL number MFCD00038640

  •  PubChem Substance ID 24898185

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Neuropeptides, Peptides and Proteins, Peptides for Cell Biology,
InChI Key   XNSAINXGIQZQOO-SRVKXCTJSA-N
assay   ≥98% (HPLC)
form   powder
storage temp.   −20°C
Gene Information   human ... TRH(7200)
mouse ... Trhr(22045)

Description

Amino Acid Sequence

Glp-His-Pro-NH2

Biochem/physiol Actions

Stimulates the production of thyrotropin (TSH) and its secretion from the anterior pituitary.

Thyrotropin releasing hormone (TRH) stimulates production and secretion of thyrotropin (TSH) and prolactin from the anterior pituitary. It also plays a vital role as a neurotransmitter and neuromodulator.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

General description

Thyrotropin releasing hormone (TRH) is a tripeptide hypothalamic regulatory hormone, encoded by the gene mapped to human chromosome 3q13.3-q21. TRH is expressed in a variety of organs including central nervous system (CNS) and gastrointestinal tract.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. P1319.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Price and Availability


Amplified Detection

All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
TW3580000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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