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P1391 Sigma

Phosphatase, Alkaline from human placenta

≥1 unit/mg solid (in glycine buffer)

Synonym: Orthophosphoric-monoester phosphohydrolase (alkaline optimum)

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Description

Analysis Note

Protein determined by biuret.

Unit Definition

One unit will hydrolyze 1.0 μmole of 4-nitrophenyl phosphate per minute at pH 10.4 at 37 ° C.

Application

Human placental alkaline phosphatase has been studied extensively due to its ectopic exptression in tumors. It has also been used in a study to investigate whether alkaline phosphatase of human tumor tissue corresponds to one or more phases of trophoblastic development.

General description

Placental alkaline phosphatase is found expressed in liver and intestines.

Price and Availability


Biomedical Applications
Safety & Documentation

Safety Information

WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Related Content

Enzymes & Proteins

Application Index | Enzyme Index | Substrate Index | Inhibitor Index | Cofactor Index | Lectin Index
Keywords: Cell signaling, Diagnostic, Drug discovery, Molecular biology

Peer-Reviewed Papers
15

References

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substrate

Product #

Description

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N2770 SIGMAFAST p-Nitrophenyl phosphate Tablets, tablet, To prepare 20 mL
N1891 SIGMAFAST p-Nitrophenyl phosphate Tablets, tablet, To prepare 5 mL
M3168 4-Methylumbelliferyl phosphate (4-MUP) Liquid Substrate System, liquid

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