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P1490 Sigma

Pepsinogen I human

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Properties

Related Categories Application Index, Biochemicals and Reagents, Enzymes, Inhibitors, and Substrates, Proteases, Proteases & Protein Sequencing More...
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... PGA3(643834), PGA4(643847), PGA5(5222), PGC(5225)

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Biochem/physiol Actions

Studies show that smoking has an effect on the level of pepsinogen I present in serum in a H. pylori-dependent manner. Patients with lower titer levels had higher levels of pepsinogen I.

Used as a control in ELISA.

Physical form

0.2 μm filtered solution in Tris chloride, pH 8.5

Price and Availability


Biomedical Applications
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1

Documents

Certificate of Analysis

Certificate of Origin

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
What is the molecular weight for Pepsinogen from human, Product P1490?
The UniProt accession number is P0DJD7. Uniprot provides a molecular weight of 41,977, based on a 388 amino acid sequence. Please see: http://www.uniprot.org/uniprot/P0DJD7 Note that pepsinogen is the full-length protein. This can be processed (removing the first 62 amino acids), to generate the active enzyme Pepsin. Please note that Sigma does not determine the sequence,  molecular weight nor the purity for  product P1490. This enzyme is released on the basis of the specific activity as noted on the specification sheet at our website.
What is the source tissue for Product P1490, Pepsinogen I from human?
The biological source of pepsinogen I human is human stomach. This information is provided on the lot specific Certificate of Origin (CofO) located at our website.
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Protocols & Articles
Peer-Reviewed Papers
15

References

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