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  • P1491 - Anti-phospho-p38 (pThr180/pTyr182) antibody produced in rabbit

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P1491 Sigma

Anti-phospho-p38 (pThr180/pTyr182) antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

Synonym: SAPKJ/MAPK, Stress Activated Protein Kinase/MAP Kinase

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology, Antibodies to Phosphoproteins at Phosphothreonine (pThr),
species reactivity   human, monkey, rat, mouse, carp, canine
application(s)   immunohistochemistry: suitable
  western blot: 1:1000
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous glycerol solution
mol wt   antibody apparent mol wt ~43 kDa
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... MAPK14(1432)
mouse ... Mapk14(26416)
rat ... Mapk14(81649)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic phosphopeptide derived from the region of p38 that contains threonine180 and tyrosine182 based on the human sequence.

General description

P38 is a mitogen-activated protein kinase (MAPK) that belongs to serine/threonine protein kinase family and is a member of the stress-activated protein kinases (SAPK). P38 signaling pathway regulates inflammatory responses, apoptosis, cell proliferation and differentiation. Dually phosphorylated p38 (i.e (Thr180) and (Tyr182)) is a 43kD endogenous protein that belongs to High Osmolarity Glycerol response kinase (HOG). Anti-phospho-p38 (pThr180/pTyr182) antibody can be used in immunostaining and immunohistochemistry. Rabbit anti-phospho-p38 (pThr180/pTyr182) antibody reacts specifically with p38 of rat and human. This product is also reactive for endogenous, active forms of p38 α, β, γ (43kD).

Physical form

Solution in Dulbecco′s phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3 with 50% glycerol, 1 mg/ml BSA and 0.05% sodium azide as a preservative.

Application

Anti-phospho-p38 (pThr180/pTyr182) antibody can be used in immunofluorescence. It can also be used in western blotting (diluted 1: 1000).

Price and Availability


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