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P152 Sigma

S(–)-Pindolol

solid

  • CAS Number 26328-11-0

  • Empirical Formula (Hill Notation) C14H20N2O2

  • Molecular Weight 248.32

  •  MDL number MFCD00153863

  •  PubChem Substance ID 24278026

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Properties

Related Categories Adrenergics, Adrenergics - Antagonists, Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index,
InChI Key   JZQKKSLKJUAGIC-NSHDSACASA-N
form   solid
optical activity   [α]23/D −4.38°, c = 1% in methanol(lit.)
color   white
solubility   0.1 M NaOH: soluble0.2 mg/mL
  methanol: soluble18 mg/mL
  0.1 M HCl: soluble20 mg/mL
  45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble3.4 mg/mL
  H2O: insoluble
originator   Novartis
Gene Information   human ... ADRB1(153), HTR1A(3350), HTR1B(3351)

Description

Biochem/physiol Actions

β1-adrenoceptor antagonist; putative 5-HT1A serotonin receptor agonist; vasodilator. Active enantiomer of pindolol.

Packaging

25, 100 mg in poly bottle

5 mg in glass bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


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Making Headway

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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