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P1584 Sigma

Peptidyl Arginine Deiminase from rabbit skeletal muscle

buffered aqueous glycerol solution, ≥200 units/mg protein (Bradford)

Synonym: Protein arginine iminohydrolase

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Description

General description

Peptidyl arginine deiminase is the enzyme that converts arginine into citrulline.

Packaging

25 units in poly bottle

Unit Definition

One unit will produce 1 μmole of N-α-benzoylcitrulline ethyl ester from BAEE per hr at 55 °C at pH 7.2.

Physical form

Solution in 20 mM Tris-HCl, pH 7.4, containing 10 mM 2-mercaptoethanol, 1 mM EDTA and 10% glycerol

Application

Peptidyl arginine deiminase has been used in a study that assessed promising novel biomarkers for the early diagnosis of rheumatoid arthritis. It has also been used in a study to investigate the autopathogenic correlation of periodontitis and rheumatoid arthritis.

Biochem/physiol Actions

Calcium is required for peptidylarginine deiminase activity in vitro.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Related Content

Enzymes & Proteins

Application Index | Enzyme Index | Substrate Index | Inhibitor Index | Cofactor Index | Lectin Index
Keywords: Cell signaling, Diagnostic, Drug discovery, Molecular biology

Peer-Reviewed Papers
15

References

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