EMAIL THIS PAGE TO A FRIEND

P1585 Sigma

PMA

for use in molecular biology applications

Synonym: 12-O-Tetradecanoylphorbol 13-acetate, 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate, PMA, Phorbol 12-myristate 13-acetate, TPA

Properties

Related Categories Bioactive Small Molecules, Biochemicals, Cell Biology, Molecular Biology, Molecular Biology Reagents,
grade   for molecular biology
assay   ≥99% (TLC)
form   film
storage condition   protect from light
solubility   DMSO: soluble (DMSO solutions can be stored dark at −20 °C for at least six months.)
  ethanol: soluble
storage temp.   −20°C

Description

Frequently Asked Questions

Live Chat and Frequently Asked Questions are available for this Product.

Biochem/physiol Actions

Potent tumor promoter; activates protein kinase C in vivo and in vitro.

Caution

Photosensitive, protect from light.

Application

Suitable for
• molecular biology studies as standard
• analytical studies of tumor promoters
• promotion of cell growth

General description

PMA (Phorbol 12-myristate 13-acetate) is an activator of protein kinase C (PKC) and a known tumor promoting agent. PMA also exhibits clastogenic (chromosome-breaking) activity.1

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



Additional Products to Explore

Brefeldin A

from Penicillium brefeldianum, ≥99% (HPLC and TLC)

Ionomycin calcium salt

Ready Made Solution, from Streptomyces conglobatus, 1 mM in DMSO, 0.2 μm filtered

Lipopolysaccharides from <I>Escherichia coli</I> 0111:B4

purified by phenol extraction

Customers Also Viewed

Ionomycin calcium salt

Ready Made Solution, from Streptomyces conglobatus, 1 mM in DMSO, 0.2 μm filtered

Phorbol 12-myristate 13-acetate

synthetic, ≥98.0% (TLC)

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?