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P1784 Sigma

Pentoxifylline

solid

Synonym: 3,7-Dimethyl-1-(5-oxohexyl)xanthine, Trental

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Properties

Related Categories Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   MQGNNJQTNFHNHK-UHFFFAOYSA-N
form   solid
color   white
solubility   H2O: ≥43 mg/mL
originator   Sanofi Aventis
Gene Information   human ... ADORA2B(136), LITAF(9516), PDE4B(5142), TNF(7124)
rat ... Tnf(24835)

Description

Biochem/physiol Actions

Phosphodiesterase inhibitor; inhibits synthesis of tumor necrosis factor α (TNF-α).

Features and Benefits

This compound is a featured product for Cyclic Nucleotide research. Click here to discover more featured Cyclic Nucleotide products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Histamine Synthesis and Metabolism and Phosphodiesterases pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
XH2475000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Discover Bioactive Small Molecules for Cyclic Nucleotides

Transmission of an extracellular signal across the cell membrane is initiated by activation of many types of hormone and neurotransmitter receptors, such as G-protein coupled receptors (GPCRs), and c...
Keywords: Antivirals, Cancer, Cardiovascular, Cellular processes, Diabetes, Diseases, Hormones, Neurotransmitters

Peer-Reviewed Papers
15

References

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