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P207 Sigma

Philanthotoxin 433 tris(trifluoroacetate) salt

≥98% (HPLC), powder

Synonym: (S)-N-[4-[[3-[(3-Aminopropyl)amino]propyl]amino]butyl]-4-hydroxy-α-[(1-oxobutyl)amino]benzenepropanamide tris(trifluoroacetate) salt, PhTX-433 tris(trifluoroacetate) salt

  • CAS Number 276684-27-6

  • Empirical Formula (Hill Notation) C23H41N5O3 · 3C2HF3O2

  • Molecular Weight 777.67

  •  MDL number MFCD00661076

  •  PubChem Substance ID 24898269

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Neurobiology, Neuroscience, Pharmacologicals,
InChI Key   UROZAUWUTBOQNV-YDULTXHLSA-N
assay   ≥98% (HPLC)
form   powder
storage condition   desiccated
color   white to beige
solubility   H2O: ≥10 mg/mL
storage temp.   −20°C
Gene Information   human ... GRIN1(2902)
mouse ... GRIN1(14810)
rat ... GRIN1(24408)

Description

Biochem/physiol Actions

Philanthotoxin 433 is a polyamine-containing toxin, which blocks NMDA-gated ion channels; originally isolated from the venom of the wasp Philanthus triangulum.

Caution

hygroscopic

Legal Information

Sold under license from Columbia University.

Reconstitution

Addition of 1 mL of solvent to vial yields a 1 mM solution.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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