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P2191 Sigma


lactide:glycolide (50:50), mol wt 30,000-60,000

Synonym: LACTEL® B6010-2, PLGA



Frequently Asked Questions

Frequently Asked Questions are available for this Product.


1, 5 g in poly bottle

Physical form

Biocompatible, biodegradable polymer.

Features and Benefits

Controlled release of bioactive agents, sutures and bioabsorbable implantable devices.

Legal Information

Lactel is a registered trademark of Durect Corp.

Price and Availability

The Future of Bioimaging

All labs need water
Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
>230 °F
Flash Point(C) 
>110 °C


Certificate of Analysis

Certificate of Origin

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
Product P2191, Poly(D,L-lactide-co-glycolide), is a compound that is useful as a time-release agent in delivery systems such as herbicides, pesticides, and drugs.  What is the rate of degradation?
The higher the lactic acid to glycolic acid ratio, the slower is the degradation rate of the polymer.  Molecular weight of the polymer is a contributing factor to the degradation; the lower the molecular weight, the faster the degradation rate of the polymer.  
What is the glass transition temperature of Product P2191, Poly(D,L-lactide-co-glycolide)?
The glass transition is 45-50°C; the melting point is amorphous.
What is the viscosity of Product P2191, Poly(D,L-lactide-co-glycolide)?
The viscosity of this product is lot-specific and can be found in the Certificate of Analysis.  A link to this document exists on the product landing page: http://www.sigmaaldrich.com/catalog/search/ProductDetail/SIGMA/P2191
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
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Protocols & Articles


Biomaterials Tutorial

Biocompatible Polymers Biodegradable Polymers Crosslinkers Biocompatible Inorganic Materials Supramolecular Chemistry
Keywords: Agriculture, Antimicrobials, Biomaterials, Ceramics, Chromatography, Cosmetics, Degradations, Diffusion, Environmental, Genomics, Germination, Nanomaterials, Oxidations, Petrochemical, Pharmaceutical, Polymerization reactions, Proteomics, Reductions

Peer-Reviewed Papers


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