• USA Home
  • P2859 - Monoclonal Anti-p300/CBP antibody produced in mouse

P2859 Sigma

Monoclonal Anti-p300/CBP antibody produced in mouse

clone NM11, purified from hybridoma cell culture

Synonym: Anti-CREB Binding Protein



Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Chromatin Remodeling, Antibodies for Gene Regulation,
species reactivity   human, mink, rat, monkey, mouse
application(s)   immunocytochemistry: suitable
  immunoprecipitation1,2: suitable
  microarray: suitable
  western blot1,2: 10-20 μg/mL using human 293 embryonal kidney cells
clone   NM11, monoclonal
concentration   ~2 mg/mL
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgG1
mol wt   antigen mol wt 300 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... KAT2B(8850)
mouse ... Kat2b(18519)
rat ... Pcaf(301164)
biological source   mouse
conjugate   unconjugated



native human p300.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.


Reacts specifically with both p300 and CBP but not with the related p270 molecule. The epitope recognized by the antibody resides within the 21 amino acid stretch spanning amino acids 2071-2091 near the CBP C-terminus. CBP and p300 differ by three noncontiguous residues within this 21 amino acid region, a difference that does not detectably affect the reactivity of the antibody.

Price and Availability

Antibody Explorer

Explore with Confidence
Safety & Documentation

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
Protocols & Articles


Antibodies to Histone Modifying Enzymes

Regulation of gene expression is mediated by several mechanisms including DNA methylation, ATP-dependent chromatin remodeling, and posttranslational modifications of histones. One of the major modifi...
Keywords: Acetylations, Gene expression, Methylations

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Inflammation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers


Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?