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P2988 Sigma

Pharmacology of Cytokines

  •  ISBN-10 0-19-850042-4

  •  ISBN-13 978-0-19-850042-1



Related Categories Books and Software, Cell Signaling Books, Immunology Books, Labware
publication info   A. Mantovani, et al., Oxford University Press, 2000, 344 pp., soft cover
mfr. no.   Oxford University Press


General description

Modulation of production and action of cytokines has been the object of intense research. This book overviews the field of cytokine research and describes the various approaches that have been taken to develop the pharmacology of these novel mediators. The book in the framework of the immunobiology of cytokines, examines interactions with the cytokine system of a variety of compounds ranging from simple synthetic chemicals to biotechnological products. It analyzes specific contexts for the pathophysiology of these mediators as well as pharmacological approaches for their control.

Table of Contents

1. Cytokines: a world apart?
Part 1 Pharmacology
2. Inhibitors of cytokine production and action
3. Inhibitors of cytokine processing
4. Receptor antagonists
5. Antibodies and soluble receptors
6. Anti-inflammatory/immunosuppressive cytokines
7. Pharmacology of chemokines
Part II Pharmacology in a context
8. Nervous System
9. Cardiovascular system
10. Cancer
11. Liver and lung
12. Skin
13. Septic shock
Appendix: Mechanisms of action and clinical uses of Type I interferons

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