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P3088 Sigma

Monoclonal Anti-Parvalbumin antibody produced in mouse

clone PARV-19, ascites fluid

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Intracellular Calcium Signaling, Antibodies to Calcium-Associated Proteins,
antibody form   ascites fluid
clone   PARV-19, monoclonal
mol wt   antigen mol wt 12 kDa
contains   15 mM sodium azide
species reactivity   human, feline, bovine, rat, frog, goat, fish, pig, canine, rabbit
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:2,000 using formalin-fixed, paraffin-embedded rat tongue or cerebellum sections
  indirect ELISA: suitable
  western blot: suitable
isotype   IgG1
conjugate   unconjugated
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... PVALB(5816)
rat ... Pvalb(25269)

Description

Immunogen

frog muscle parvalbumin.

Specificity

Recognizes parvalbumin in a Ca2+ ion-dependent manner. Does not react with other members of the EF-hand family such as calmodulin, intestinal calcium-binding protein, S100A2 (S100L), S100A6 (calcyclin), the α chain of S-100 (i.e. in S-100a and S-100ao), or the β chain (i.e. in S-100a and S-100b).

Price and Availability

TruPAGE™ Pre-cast Polyacrylamide Gels


TruPAGE™ Pre-cast Polyacrylamide GelsTruPAGE Gels run true every time!

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Monoclonal Anti-Parvalbumin antibody produced in mouse

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Safety & Documentation

Safety Information

Hazard Codes (Europe) 
Xn
Risk Statements (Europe) 
22

Protocols & Articles

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Keywords: Buffers, Cell biology, Epigenetics, Immunohistochemistry, Immunoprecipitation, Molecular biology, Neuroscience, Western blot

Peer-Reviewed Papers

References

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Decreased number of parvalbumin and cholinergic interneurons in the striatum of individuals with Tourette syndrome. Kataoka, Y., et al. J. Comp. Neurol. 518, 277-91, (2010)

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Projections of preBÃ tzinger complex neurons in adult rats. Tan, W., et al. J. Comp. Neurol. 518, 1862-78, (2010)

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Extracellular matrix-glial abnormalities in the amygdala and entorhinal cortex of subjects diagnosed with schizophrenia. Pantazopoulos, H., et al. Arch. Gen. Psychiatry 67, 155-66, (2010)

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Hippocampal interneurons in bipolar disorder. Konradi, C., et al. Arch. Gen. Psychiatry 68, 340-50, (2011)

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Rapid hair cell loss: a mouse model for cochlear lesions. Taylor RR J. Assoc. Res. Otolaryngol. 9(1), 44-64, (2008)

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Fgfr2 Is Required For The Development Of The Medial Prefrontal Cortex And Its Connections With Limbic Circuits Stevens, H.E., et al. J. Neurosci. 30, 5590 - 5602, (2010)

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Matrix-binding vascular endothelial growth factor (VEGF) isoforms guide granule cell migration in the cerebellum via VEGF receptor Flk1. Ruiz de Almodovar, C., et al. J. Neurosci. 30, 15052-66, (2010)

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Colocalization of hyperpolarization-activated, cyclic nucleotide-gated channel subunits in rat retinal ganglion cells. Stradleigh, T.W., et al. J. Comp. Neurol. 519, 2546-73, (2011)

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Ivy and neurogliaform interneurons are a major target of µ-opioid receptor modulation. Krook-Magnuson, E., et al. J. Neurosci. 31, 14861-70, (2011)

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Decreased rhythmic GABAergic septal activity and memory-associated theta oscillations after hippocampal amyloid-beta pathology in the rat. Villette, V., et al. J. Neurosci. 30, 10991-1003, (2010)

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Cntnap4 differentially contributes to GABAergic and dopaminergic synaptic transmission. Karayannis T, Au E, Patel JC, et al. Nature 511(7508), 236-40, (2014)

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Activin potentiates proliferation in mature avian auditory sensory epithelium. McCullar, J.S., et al. J. Neurosci. 30, 478-90, (2010)

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Deletion Of CREB1 From The Dorsal Telencephalon Reduces Motivational Properties Of Cocaine McPherson, C.S., et al. Cereb. Cortex 20, 941 - 952, (2010)

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Cell-poor septa separate representations of digits in the ventroposterior nucleus of the thalamus in monkeys and prosimian galagos. Qi, H.X., et al. J. Comp. Neurol. 519, 738-58, (2011)

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Subpopulations of cholinergic, GABAergic and glutamatergic neurons in the pedunculopontine nucleus contain calcium-binding proteins and are heterogeneously distributed. Martinez-Gonzalez, C., et al. Eur. J. Neurosci. 35, 723-34, (2012)

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Multiple anxiogenic drugs recruit a parvalbumin-containing subpopulation of GABAergic interneurons in the basolateral amygdala. Hale, M.W., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry 34, 1285-93, (2010)

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BACE1 Elevation is Involved in Amyloid Plaque Development in the Triple Transgenic Model of Alzheimer's Disease: Differential Aβ Antibody Labeling of Early-Onset Axon Terminal Pathology. Cai, Y., et al. Neurotox. Res. 21, 160-74, (2012)

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Dendritic A-type potassium channel subunit expression in CA1 hippocampal interneurons Vacher, H., et al. Neuroscience 5, 71-76, (2008)

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Distinct neural pathways mediate α7 nicotinic acetylcholine receptor-dependent activation of the forebrain. Thomsen, M.S., et al. Cereb. Cortex 20, 2092-102, (2010)

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Hedgehog controls neural stem cells through p53-independent regulation of Nanog. Po, A., et al. EMBO J. 29, 2646-58, (2010)

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An Improved BAC Transgenic Fluorescent Reporter Line for Sensitive and Specific Identification of Striatonigral Medium Spiny Neurons. Ade, K.K., et al. Front. Syst. Neurosci. 5, 32, (2011)

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Structural and immunochemical characteristics of the neuronal organization of field 4 of the sensorimotor cortex in cats. Neurosci. Behav. Physiol. 40, 687-92, (2010)

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Failure of NMDA receptor hypofunction to induce a pathological reduction in PV-positive GABAergic cell markers. Benneyworth, M.A., et al. Neurosci. Lett. 488, 267-71, (2011)

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Direct excitation of parvalbumin-positive interneurons by M1 muscarinic acetylcholine receptors: roles in cellular excitability, inhibitory transmission and cognition. Yi F, Ball J, Stoll KE, et al. J. Physiol. 592(Pt 16), 3463-94, (2014)

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Expression of PTPRO in the interneurons of adult mouse olfactory bulb. Kotani, T., et al. J. Comp. Neurol. 518, 119-36, (2010)

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Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia. Carlson, G.C., et al. Proc. Natl. Acad. Sci. U. S. A. 108, E962-70, (2011)

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A blueprint for the spatiotemporal origins of mouse hippocampal interneuron diversity. Tricoire, L., et al. J. Neurosci. 31, 10948-70, (2011)

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Distribution and role of Kv3.1b in neurons in the medial septum diagonal band complex. Henderson, Z., et al. Neuroscience 166, 952-69, (2010)

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Retinal input to efferent target amacrine cells in the avian retina. Lindstrom, S.H., et al. Vis. Neurosci. 27, 103-18, (2010)

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Interneurons in the developing human neocortex. Zecevic, N., et al. Dev. Neurobiol. 71, 18-33, (2011)

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Role of nucleus accumbens shell neuronal ensembles in context-induced reinstatement of cocaine-seeking. Cruz FC, Babin KR, Leao RM, et al. J. Neurosci. 34(22), 7437-46, (2014)

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A DNA variant within the MYO7A promoter regulates YY1 transcription factor binding and gene expression serving as a potential dominant DFNA11 auditory genetic modifier. Street, V.A., et al. J. Biol. Chem. 286, 15278-86, (2011)

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Immunolocalization of gap junction protein connexin43 (GJA1) in the human retina and optic nerve. Kerr, N.M., et al. Invest. Ophthalmol. Vis. Sci. 51, 4028-34, (2010)

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Pre- and postsynaptic effects of norepinephrine on γ-aminobutyric acid-mediated synaptic transmission in layer 2/3 of the rat auditory cortex. Salgado, H., et al. Synapse 66, 20-8, (2012)

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Functional activation of glutamate ionotropic receptors in the human peripheral retina. de Souza, C.F., et al. Exp. Eye Res. 94, 71-84, (2012)

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Heterogeneity of parvalbumin expression in the avian cerebellar cortex and comparisons with zebrin II. Wylie, D.R., et al. Neuroscience 185, 73-84, (2011)

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GABAergic synapses made by a retinal dopaminergic neuron Raviola, M.C. Proc. Natl. Acad. Sci. U. S. A. 100, 1358-1363, (2003)

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Neonatal cerebral hypoxia-ischemia impairs plasticity in rat visual cortex. Failor, S., et al. J. Neurosci. 30, 81-92, (2010)

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System-wide immunohistochemical analysis of protein co-localization. Kim, M., et al. PLoS ONE 7, e32043, (2012)

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β-Secretase-1 elevation in aged monkey and Alzheimer's disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and β-amyloid accumulation. Cai, Y., et al. Eur. J. Neurosci. 32, 1223-38, (2010)

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Functional deprivation promotes amyloid plaque pathogenesis in Tg2576 mouse olfactory bulb and piriform cortex. Zhang, X.M., et al. Eur. J. Neurosci. 31, 710-21, (2010)

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Nuclear lamins are differentially expressed in retinal neurons of the adult rat retina. Wakabayashi, T., et al. Histochem. Cell Biol. 136, 427-36, (2011)

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The sand rat, Psammomys obesus, develops type 2 diabetic retinopathy similar to humans. Saïdi, T., et al. Invest. Ophthalmol. Vis. Sci. 52, 8993-9004, (2011)

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Reciprocal regulation of epileptiform neuronal oscillations and electrical synapses in the rat hippocampus. Kinjo ER, Higa GS, Morya E, et al. PLoS ONE 9(10), e109149, (2014)

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Parvalbumin interneurons and calretinin fibers arising from the thalamic nucleus reuniens degenerate in the subiculum after kainic acid-induced seizures. Drexel, M., et al. Neuroscience 189, 316-29, (2011)

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Genesis of Neuronal and Glial Progenitors in the Cerebellar Cortex of Peripuberal and Adult Rabbits Ponti, G., et al. PLoS ONE 3, e2366, (2008)

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Fcgamma receptors contribute to pyramidal cell death in the mouse hippocampus following local kainic acid injection. Suemitsu, S., et al. Neuroscience 166, 819-31, (2010)

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Elfn1 recruits presynaptic mGluR7 in trans and its loss results in seizures. Tomioka NH, Yasuda H, Miyamoto H, et al. Nat. Commun. 5, 4501, (2014)

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GABAergic neurons in the medial septum-diagonal band of Broca (MSDB) are important for acquisition of the classically conditioned eyeblink response. Roland JJ, Janke KL, Servatius RJ, et al. Brain Struct. Funct. 219(4), 1231-7, (2014)

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Recovery of functional and structural age-related changes in the rat primary auditory cortex with operant training. de Villers-Sidani, E., et al. Proc. Natl. Acad. Sci. U. S. A. 107, 13900-5, (2010)

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GABAB receptors in maintenance of neocortical circuit function. Sebe JY, Looke-Stewart E, and Baraban SC Exp. Neurol. 261, 163-70, (2014)

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Functional endothelin receptors are selectively expressed in isolectin B4-negative sensory neurons and are upregulated in isolectin B4-positive neurons by neurturin and glia-derived neurotropic factor. Vellani, V., et al. Brain Res. 1381, 31-7, (2011)

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