|Related Categories||Antioxidants and Cytoprotectants, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cell Stress,|
|solubility||ethanol: soluble50 mg/mL|
100, 500 g in poly bottle
Prepare a 0.1M solution in glycerol:PBS (9:1)
Used as an anti-fade reagent in fluorescence microscopy to reduce photobleaching of fluorescent probes such as rhodamine and fluorescein.
An antioxidant that exhibits antimicrobial activity. Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both in vitro and in vivo. It has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis. However, propyl gallate induced single strand breaks in DNA at concentrations higher than 0.25 μM when it was combined with copper concentrations at 5 μM and above. Another report, however, found that incubation of isolated rat hepatocytes with propyl gallate at concentrations of >1 mM induced cell killing, whereas, a lower concentration of propyl gallate > 0.5 mM resulted in a ladder formation of soluble low-molecular weight DNA fragments, characteristic of apoptosis.
An antioxidant that exhibits antimicrobial activity. Propyl gallate has been reported to be an effective antioxidant-based hepatoprotector, both in vitro and in vivo. It has also been shown to prevent neuronal apoptosis and block the death of neurons exposed to FeSO4/GA as well as partially protect endothelial cells against TNF-induced apoptosis.
Certificate of Analysis
Certificate of Origin
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Faceshields, Gloves|
|Hazard Codes (Europe)||Xn|
|Risk Statements (Europe)||22-43|
|Safety Statements (Europe)||24-37|
|Flash Point(F)||368.6 °F|
|Flash Point(C)||187 °C|
Characterization of a tannase from Emericella nidulans immobilized on ionic and covalent supports for propyl gallate synthesis. Gonçalves HB, Jorge JA, Pessela BC, et al. Biotechnol. Lett. 35(4), 591-8, (2013)
Propyl gallate plays a nephroprotective role in early stage of diabetic nephropathy associated with suppression of glomerular endothelial cell proliferation and angiogenesis. Tian S, Tang J, Liu H, et al. Exp. Diabetes Res. 2012, 209567, (2012)
Effects of emulsifier hydrophile-lipophile balance and emulsifier concentration on the distributions of gallic acid, propyl gallate, and α-tocopherol in corn oil emulsions. Losada-Barreiro S, Sánchez-Paz V, and Bravo-Díaz C J. Colloid. Interface Sci. 389(1), 1-9, (2013)
Characterization of bioimprinted tannase and its kinetic and thermodynamics properties in synthesis of propyl gallate by transesterification in anhydrous medium. Nie G, Zheng Z, Gong G, et al. Appl. Biochem. Biotechnol. 167(8), 2305-17, (2012)
Utility of 4-chloro-7-nitrobenzofurazan for the spectrofluorimetric determination of butylated hydroxyanisole and propyl gallate in foodstuffs. Chen M, Tai Z, Hu X, et al. J. Food Sci. 77(4), C401-7, (2012)
A target analogue imprinted polymer for the recognition of antiplatelet active ingredients in Radix Salviae Miltiorrhizae by LC/MS/MS. Huang M, Pang W, Zhang J, et al. J. Pharm. Biomed. Anal. 58, 12-8, (2012)
[Mechanism of the reduction of cerebral ischemic-reperfusion injury through inhibiting the activity of NF-kappaB by propyl gallate]. Zheng JM, Chen XC, Lin M, et al. Yao Xue Xue Bao 46(2), 158-64, (2011)
Cloud-point extraction and reversed-phase high-performance liquid chromatography for the determination of synthetic phenolic antioxidants in edible oils. Chen M, Xia Q, Liu M, et al. J. Food Sci. 76(1), C98-103, (2011)
Propyl gallate synthesis using acidophilic tannase and simultaneous production of tannase and gallic acid by marine Aspergillus awamori BTMFW032. Beena PS, Basheer SM, Bhat SG, et al. Appl. Biochem. Biotechnol. 164(5), 612-28, (2011)
Anti-oxidant and anti-bacterial activities of novel N'-arylmethylidene-2-(3, 4-dimethyl-5, 5-dioxidopyrazolo[4,3-c][1,2]benzothiazin-2(4H)-yl) acetohydrazides. Matloob Ahmad et al Eur. J. Med. Chem. 45, 698-704, (2010)
Astrocytic gap junctional communication decreases neuronal vulnerability to oxidative stress-induced disruption of Ca2+ homeostasis and cell death. Blanc, E.M., et al. J. Neurochem. 70, 958-970, (1998)
Linoleic acid potentiates TNF-mediated oxidative stress, disruption of calcium homeostasis, and apoptosis of cultured vascular endothelial cells. Toborek, M., et al. J. Lipid Res. 38, 2155-2167, (1997)
Aldrich MSDS 1, 1552:C / Arctander, 2710 / Corp MSDS 1 (2), 2967:D / FT-IR 1 (2), 301:A / FT-IR 2 (2), 2854:D / FT-NMR 1 (2), 1261:B / Fenaroli, 698 / IR-Spectra (3), 1032:D / IR-Spectra (2), 903:G / NMR-Reference 2 (2), 295:A / RegBook 1 (2), 1909:K / Sax 6, 2310 / Sigma FT-IR 1 (2), 862:C / Structure Index 1, 306:D:5 / Vapor Phase 3, 1370:B
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