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Principles and Practice of Biological Mass Spectrometry

  •  ISBN-10 0-471-33053-1

  •  ISBN-13 978-0-471-33053-0

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publication info   C. Dass, Wiley-Interscience, 2001, 416 pp., hard cover
mfr. no.   Wiley

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General description

Beginning with a review of fundamentals and recent developments in biological mass spectrometry instrumentation, this book contains well-illustrated instances of important techniques that includes tandem mass spectrometry, collision-induced dissociation, molecular mass determination, coupling of mass spectrometry with separation techniques, and quantitation. Contemporary approaches to characterization of various classes of compounds is provided along with numerous examples of applications.

Table of Contents

Introduction to Mass Spectrometry.
Ionization Methods.
Mass Analysis and Ion Detection.
Tandem Mass Spectrometry.
Molecular Mass Measurement.
Quantitative Analysis.
Coupling of Separation Techniques with Mass Spectrometry.
Structural Analysis of Proteins.
Structural Characterization of Peptides.
Analysis of Glycoproteins and Oligosaccharides.
Folding—Unfolding and Higher-order Structures of Proteins.
Investigation of Noncovalent Interactions.
Structure Determination of Lipids and Glycolipids.
Screening Combinatorial Libraries.
Characterization of Oligonucleotides.
Applications to Real-World Problems.
Index.

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