|Related Categories||Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones,|
Suitable as an inducer of ecdysone-inducible mammalian expression system.
Ponasterone A is an insect hormone, involved in regulating metamorphosis.
Ecdysteroid receptor from the American lobster Homarus americanus: EcR/RXR isoform cloning and ligand-binding properties. Tarrant AM, Behrendt L, Stegeman JJ, et al. Gen. Comp. Endocrinol. 173(2), 346-55, (2011)
Isoforms of the heteropteran Nezara viridula ecdysone receptor: protein characterisation, RH5992 insecticide binding and homology modelling. Tohidi-Esfahani D, Lawrence MC, Graham LD, et al. Pest Manag. Sci. 67(11), 1457-67, (2011)
Hemolymph ecdysteroids during the last three molt cycles of the blue crab, Callinectes sapidus: quantitative and qualitative analyses and regulation. Chung JS Arch. Insect Biochem. Physiol. 73(1), 1-13, (2010)
Sequencing and structural homology modeling of the ecdysone receptor in two chrysopids used in biological control of pest insects. Zotti MJ, Christiaens O, Rougé P, et al. Ecotoxicology 21(3), 906-18, (2012)
Genome-wide examination of the transcriptional response to ecdysteroids 20-hydroxyecdysone and ponasterone A in Drosophila melanogaster. Gonsalves SE, Neal SJ, Kehoe AS, et al. BMC Genomics 12, 475, (2011)
The brown shrimp (Crangon crangon L.) ecdysteroid receptor complex: cloning, structural modeling of the ligand-binding domain and functional expression in an EcR-deficient Drosophila cell line. Verhaegen Y, Parmentier K, Swevers L, et al. Gen. Comp. Endocrinol. 168(3), 415-23, (2010)
Inhibition of secretion of interleukin (IL)-12/IL-23 family cytokines by 4-trifluoromethyl-celecoxib is coupled to degradation via the endoplasmic reticulum stress protein HERP. McLaughlin M, Alloza I, Quoc HP, et al. J. Biol. Chem. 285(10), 6960-9, (2010)
Insulin-like growth factor binding protein-3 induces G1 cell cycle arrest with inhibition of cyclin-dependent kinase 2 and 4 in MCF-7 human breast cancer cells. Kim HS, Lee WJ, Lee SW, et al. Horm. Metab. Res. 42(3), 165-72, (2010)
A quantitative affinity-profiling system that reveals distinct CD4/CCR5 usage patterns among human immunodeficiency virus type 1 and simian immunodeficiency virus strains. Johnston SH, Lobritz MA, Nguyen S, et al. J. Virol. 83(21), 11016-26, (2009)
Synthesis, binding and bioactivity of gamma-methylene gamma-lactam ecdysone receptor ligands: advantages of QSAR models for flexible receptors. Woldeamanuel Birru et al Bioorg. Med. Chem. 18, 5647-60, (2010)
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