P3717 Sigma


2 mg/mL, buffered aqueous solution

Synonym: Phosphoserine Antibody Inhibitor




O-phospho-L-serine conjugated to bovine serum albumin. Phosphoserine antibody inhibitor specifically blocks the reactivity of anti-phosphoserine antibody. It does not block the activity of anti-phosphothreonine or anti-phosphotyrosine-specific antibodies. The product is useful in immunoblotting and in ELISA.
Working dilution is at least 2 μg/ml by the specific inhibition of the reactivity of Monoclonal Anti-Phosphoserine (Sigma Product No. P3430), used in immunoblotting of rat cerebral cortex extract, and in ELISA.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.


Phosphoserine-BSA may be used for specific inhibition of monoclonal anti-phosphoserine (Sigma Product No. P3430) in immunoblotting and ELISA applications, at a working dilution of 2 μg/mL.

General description

The activity of proteins depends on phosphorylation of specific amino acid residues. In applications involving identification of activated cellular proteins, it is important to confirm specificity of antibodies used against a particular phosphorylated amino acid. For such applications, inhibitors of phosphorylated antibodies on specific amino acid residues are suitable. Phosphoserine antibody inhibitor may be used for the specific inhibition of the reactivity of anti-phosphoserine antibodies but not that of anti-phosphothreonine- or anti-phosphotyrosine-specific antibodies.

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Safety Information

NONH for all modes of transport
WGK Germany 


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