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P3761 Sigma

Pentobarbital sodium salt

Synonym: 5-Ethyl-5-(1-methylbutyl)-2,4,6-trioxohexahydropyrimidine, Nembutal



Related Categories Cell Biology, Cell Signaling and Neuroscience, Neurobiology, Neuroscience, Pharmacologicals,
drug control   USDEA Schedule II; Home Office Schedule 3; psychotrope; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
solubility   H2O: soluble
  alcohol: soluble


Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Biochem/physiol Actions

Anesthetic; sedative; hypnotic; enhances GABAergic activity.

Price and Availability

All labs need water
Safety & Documentation

Safety Information

GHS06  GHS06
Signal word 
Hazard statements 
Precautionary statements 
UN 2811 6.1 / PGIII
WGK Germany 


Certificate of Analysis

Certificate of Origin

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
How can I solubilize Pentobarbital sodium salt, Product P3761?
This product is soluble in water (50 mg/ml), with heat and sonication as needed, yielding a clear to slightly hazy, colorless solution.
How can I store my solution of Pentobarbital sodium salt, Product P3761?
Solutions of the sodium salt are typically pH 9.0 - 11.0 (BP/USP). If the pH is lowered, the free acid will precipitate from solution. Solutions decompose on standing, the decomposition being accelerated at higher temperatures.  We recommend to make solutions fresh.
Is Pentobarbital sodium salt available as a solution?
We do not offer a solution of pentobarbital as it is not stable as a solution.
What is the shelf life for Pentobarbital sodium salt, Product P3761?
Product No. P3761 has a retest date of 3 years from date of manufacture.  
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
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