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P4668 Sigma

Praziquantel

anthelminic, neurogenic

Synonym: 2-(Cyclohexylcarbonyl)-1,2,3,6,7-11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics N-S, Antiparasitic / Antiprotozoal / Anthelminthic, Biochemicals and Reagents,
InChI Key   FSVJFNAIGNNGKK-UHFFFAOYSA-N
form   powder
solubility   ethanol: soluble5 mg/mL
Mode of action   cell membrane | interferes
antibiotic activity spectrum   parasites
storage temp.   −20°C

Description

Application

Praziquantel is a potent anthelmintic used against schistosome and many cestode infestations. It is used to study voltage-gated Ca2+ channels and is a potential small molecule neurogenic.

Biochem/physiol Actions

Praziquantel increases the permeability of the tegmentum to Ca2+ which results in the contraction of schistosomes and death. Praziquantel causes vacuolization and disintegration of the schistosome tegument. It is more effective on adult worms than young worms. It inhibits glucose uptake, which lowers glycogen levels and stimulates lactate release

Other Notes

1g,5g,25g

Keep container tightly closed in a dry and well-ventilated place.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
UQ4150000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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Product #

Description

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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