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P4685 Sigma

IgG1−PE Isotype Control from murine myeloma

clone MOPC 21, purified immunoglobulin, buffered aqueous solution

Synonym: IgG1 Isotype Control from murine myeloma

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Properties

Related Categories Analytical Cytology, Antibodies, Antibody Characterization and Analysis, Biochemicals and Reagents, Isotype Controls,
biological source   mouse
antibody form   purified immunoglobulin
clone   MOPC 21, monoclonal
form   buffered aqueous solution
application(s)   flow cytometry: suitable
isotype   IgG1κ
conjugate   phycoerythrin (R-PE) conjugate
shipped in   wet ice
storage temp.   2-8°C

Description

Preparation Note

Prepared by conjugation to R-phycoerythrin (PE). This orange-red dye is efficiently excited at 488 nm and emits at 578 nm.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Application

IgG1-PE Isotype Control antibodies are suitable for use in flow cytometry.

General description

Immunoglobulin G (IgG) is a glycoprotein antibody that regulates immune responses such as phagocytosis and is also involved in the development of autoimmune diseases . Mouse IgGs have four distinct isotypes, namely, IgG1, IgG2a, IgG2b, and IgG3. IgG1 regulates complement fixation in mice . IgG1-PE Isotype Control antibodies are specific for anti-mouse whole serum and anti-mouse IgG1. The product does not react with antiserum from mouse IgA, IgM, IgG2a, IgG2b, IgG3 and λ light chain.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers
15

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