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P5069 Sigma

Prostaglandin F tris salt

synthetic, cell culture tested

Synonym: (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dienoic acid tris salt, PGF−Tris

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Properties

Related Categories Allium sativum (Garlic), Biochemicals and Reagents, Cell Biology, Eicosanoids (Prostaglandins, Leukotrienes), Fatty Acyls,
biological source   synthetic
InChI Key   IYGXEHDCSOYNKY-RZHHZEQLSA-N
assay   ≥99%
suitability   cell culture tested
storage temp.   −20°C

Description

Packaging

1 mg in glass bottle

Biochem/physiol Actions

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. A positive feedback loop between endometrial PG F and luteal oxytocin is responsible for completion of luteolysis.

Luteolytic prostaglandin that induces parturition. Potent vasoconstrictor of pulmonary, coronary, and cerebral arteriole beds. Also stimulates contraction of smooth muscle, such as in bronchi, with possible involvement in asthma. This effect is at least partially mediated through tachykinin release.

Prostaglandin F2α is induced by uterine-produced oxytocin and acts on the corpus luteum to cause luteolysis and inhibit progesterone production.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
UK8025000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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