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P5109 Sigma

Prokaryotic Gene Expression

  •  ISBN-10 0-19-963603-6

  •  ISBN-13 978-0-19-963603-7

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publication info   S. Baumberg, ed., Oxford University press, 1999, 354 pp., soft cover
mfr. no.   Oxford University Press

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General description

Although prokaryotes lack a nucleus, they have genomic DNA and the study of their genes is important in areas of developmental biology and cancer along with genetic engineering and expression systems and development of antibiotics. Some topics covered are operons, protein recognition of specific DNA and RNA binding sites, variant tRNA polymerases, post-transcriptional control, prokaryotic DNA topology, switch systems, and integration of control devices.

Table of Contents

1. History and overview, Simon Baumberg
2. Protein recognition of specific DNA and RNA binding sites, Peter G. Stockley
3. Promoters, sigma factors, and variant RNA polymerases, John D. Helmann
4. Repressors and activators, Stephen J. W. Busby
5. Post-transcriptional control, Zhiping Gu and Paul S. Lovett
6. Prokaryotic DNA topology and gene expression, Karl Drlica et. al.
7. Integration of control devices: A global regulatory network in Escherichia coli, Regine Hengge-Aronis
8. Two-component systems, Mariette R. Atkinson and Alexander J. Ninfa
9. Switch systems, J. R. Saunders
10. Integration of control devices. I. Pathogenecity, Charles J. Dorman
11. Integration of control devices. II. Sporulation and antibiotic production, Michael D. Yudkin and Keith F. Chater
12. Evolution of prokaryotic regulatory systems, Simon Baumberg

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