Synonym: AMPK Inhibitor, Compound C, Dorsomorphin
Adenosine Kinase; ATP:adenosine 5-prime-phosphotransferas|
|storage condition||protect from light|
|color||white to beige|
|solubility||DMSO: >2 mg/mL (warmed)|
Dorsomorphin is a selective inhibitor of Bone morphogenetic protein (BMP) signaling. It has been found to inhibit BMP signals required for embryogenesis and promoted significant neural differentiation from human pluripotent stem cell (hPSC) lines. Dorsomorphin also acts as a potent, selective, reversible, and ATP-competitive inhibitor of AMPK (AMP-activated protein kinase); Ki = 109 nM in the presence of 5 μM ATP and the absence of AMP).
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