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P5739 Sigma

Placenta Growth Factor-2 from mouse

lyophilized powder, recombinant, expressed in baculovirus infected Sf21 cells, cell culture tested

Synonym: PGF-2, PlGF-2



Related Categories Angiogenesis, Angiogenic Factors, Cancer Research, Cell Biology, Cell Culture,
recombinant   expressed in baculovirus infected Sf21 cells
assay   >97% (SDS-PAGE)
form   lyophilized powder
mol wt   mol wt ~38 kDa by SDS-PAGE
impurities   endotoxin, tested
suitability   cell culture tested
storage temp.   −20°C
Gene Information   mouse ... Pgf(18654)


Analysis Note

The biological activity is measured by its ability to bind to immobilized Flt1/Fc chimera in ELISA.

Biochem/physiol Actions

Angiogenic factor of the VEGF family. Ligand for the VEGFR-1 (flt-1) receptor and for neuropilin-1. PlGF-2 differs from PlGF-1 and PlGF-3 in having a heparin binding domain.

Physical form

Lyophilized from a 0.2 μm filtered solution in 30% acetonitrile and 0.1% trifluoroacetic acid containing 0.5 mg bovine serum albumin.

Price and Availability

All labs need water
Safety & Documentation

Safety Information

GHS05  GHS05
Signal word 
Hazard statements 
Precautionary statements 
UN 1759 8 / PGI
WGK Germany 


Certificate of Analysis

Certificate of Origin

Protocols & Articles


VEGF Pathway

Background VEGF Pathway    Ligands    Receptors VEGF – Signal Transduction Factors Regulating VEGF and VEGFR Expression VEGFR in Human Diseases    Cancer    Preeclampsia    Age-related Macular Degene...
Keywords: AGE, Angiogenesis, Apoptosis, Cancer, Cell proliferation, Clinical, Diseases, Gene expression, Growth factors, Infrared spectroscopy, Ligands, Neurodegenerative Diseases, Phosphorylations, Transcription, Transduction

Vascular Endothelial Growth Factors (VEGF)

Vascular endothelial growth factor (VEGF) is a family of closely related growth factors having a conserved pattern of eight cysteine residues and sharing common VEGF receptors. Originally known simpl...
Jennifer Fries
BioFiles 2009, 4.5, 26.
Keywords: Angiogenesis, Gene expression, Growth factors, Inflammation, Ligands

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