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P5986 Sigma

Proteomics: From Protein Sequence to Function

  •  ISBN-10 0-387-91589-3

  •  ISBN-13 978-0-387-91589-0

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publication info   S. Pennington and M.J. Dunn, ed., Bios Scientific, 2001, 344 pp., soft cover
mfr. no.   Garland

Description

General description

Following the announcement of the draft sequence of the human genome, attention is now increasingly turning to the analysis of the proteins encoded by genomes - proteomics. This is a rapidly emerging research area and this book reviews recent developments in proteomics and compares them with current genomics technologies. The book is written by experts who review their area in a concise yet easy to understand style, providing a comprehensive review volume that integrates genomics with proteomics.

Table of Contents

Overview
1. Bridging genomics and proteomics
2. Methods for measurement of gene (mRNA) expression
3. Two-dimensional polyacrylamide gel electrophoresis for proteome analysis
4. Detecting proteins in polyacrylamide gels and on electroblot membranes
5. Mass spectrometry-based methods for protein identification and phosphorylation site analysis
6. Image analysis of two-dimensional gels
7. Enhancing high-throughput proteome analysis: the impact of stable isotope labeling
8. The automation of proteomics: technical and informatic solutions for high-throughput protein analysis
9. Message in a bottleneck: a complete approach to automating porteome analysis
10. Novel approaches to protein expression analysis
11. Application of proteome analysis to drug development and toxicology
12. Phage antibodies as tools for proteomics
13. Glycobiology and proteomics
14. Proteomics in an academic environment
15. Proteomics as tool for plant genetics and breeding
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