Synonym: (R)-(−)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride, (R)-(−)-3-Hydroxy-α-(methylaminomethyl)benzyl alcohol hydrochloride
|Related Categories||Adrenergics, Adrenergics - Agonists, Agonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules,|
|Gene Information||human ... ADRA1A(148), ADRA1B(147), ADRA1D(146)|
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5, 10, 25, 50, 100 g in glass bottle
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P261-P305 + P351 + P338|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Faceshields, Gloves|
|Hazard Codes (Europe)||Xn|
|Risk Statements (Europe)||22-36/37/38|
|Safety Statements (Europe)||26-36|
α1-Adrenoceptors are widely distributed, and are activated either by norepinephrine (A7257, A0937) released from sympathetic nerve terminals or by epinephrine (E4250, E4375) released from the adrenal...
Keywords: Apoptosis, Atomic absorption spectroscopy, Gene expression, Gluconeogenesis, Transduction
Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart. Lazou, A., et al. Biochem. J. 332, 459-465, (1998)
Role of α1-adrenoceptor subtypes in production of the positive inotropic effects in mammalian myocardium: implications for the α1-adrenoceptor subtype distribution. Hattori, Y., and Kanno, M. Life Sci. 62, 1449-1453, (1998)
The effect of high-fructose intake on the vasopressor response to angiotensin II and adrenergic agonists in Sprague-Dawley rats. Abdulla MH, Sattar MA, Abdullah NA, et al. Pak. J. Pharm. Sci. 26(4), 727-32, (2013)
Middle cerebral O₂ delivery during the modified Oxford maneuver increases with sodium nitroprusside and decreases during phenylephrine. Stewart JM, Medow MS, DelPozzi A, et al. Am. J. Physiol. Heart Circ. Physiol. 304(11), H1576-83, (2013)
Alpha1-adrenenoceptor stimulation inhibits cardiac excitation-contraction coupling through tyrosine phosphorylation of beta1-adrenoceptor. O-Uchi J, Komukai K, Kusakari Y, et al. Biochem. Biophys. Res. Commun. 433(2), 188-93, (2013)
Propofol increases vascular relaxation in aging rats chronically treated with the angiotensin-converting enzyme inhibitor captopril. Gragasin FS, Bourque SL, and Davidge ST Anesth. Analg. 116(4), 775-83, (2013)
Phenylephrine versus ephedrine on cerebral perfusion during carotid endarterectomy (PEPPER): study protocol for a randomized controlled trial. Pennekamp CW, Immink RV, Buhre WF, et al. Trials 14, 43, (2013)
Catharanthine dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. Jadhav A, Liang W, Papageorgiou PC, et al. J. Pharmacol. Exp. Ther. 345(3), 383-92, (2013)
Evaluation of the autonomic function in patients with hypertrophic cardiomyopathy with and without syncope. Macatrão-Costa MF, Arteaga-Fernandez E, de Brito FS, et al. Arq. Bras. Cardiol. 100(2), 180-6, (2013)
Effects of arginine and antioxidant vitamins on pulmonary artery reactivity to phenylephrine in the broiler chicken. Bautista-Ortega J, Stallone JN, and Ruiz-Feria CA Poult. Sci. 92(4), 1062-72, (2013)
Endothelium-dependent and independent vasorelaxant effects of aqueous extract of Tridax procumbens Lin. leaf in rat aortic rings. Salahdeen HM, Idowu GO, and Murtala BA Indian J. Exp. Biol. 50(12), 883-8, (2012)
Vasoconstrictor-induced endocytic recycling regulates focal adhesion protein localization and function in vascular smooth muscle. Poythress RH, Gallant C, Vetterkind S, et al. Am. J. Physiol. Cell Physiol. 305(2), C215-27, (2013)
B. anthracis edema toxin increases cAMP levels and inhibits phenylephrine-stimulated contraction in a rat aortic ring model. Li Y, Cui X, Solomon SB, et al. Am. J. Physiol. Heart Circ. Physiol. 305(2), H238-50, (2013)
Comparison of phenylephrine administration and exercise versus phenylephrine administration and a rolling procedure for the correction of nephrosplenic entrapment of the large colon in horses: 88 cases (2004-2010). Fultz LE, Peloso JG, Giguère S, et al. J. Am. Vet. Med. Assoc. 242(8), 1146-51, (2013)
Aldrich MSDS 1, 1467:C / Corp MSDS 1 (2), 2776:D / FT-IR 2 (2), 2177:D / FT-IR 1 (1), 1286:A / FT-NMR 1 (2), 604:B / IR-Spectra (3), 773:E / RegBook 1 (1), 1485:I / Sax 6, 1578 / Sigma FT-IR 1 (1), 697:D / Structure Index 1, 232:D:5
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