|Related Categories||Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, Antibiotics, Antibiotics A to Z,|
|impurities||<0.0005% Phosphorus (P)|
|<0.1% Insoluble matter|
|anion traces||chloride (Cl-): <0.5%|
|cation traces||Al: <0.0005%|
Pyrantel pamoate is used as a deworming agent in domesticated animals such as horses, hamsters, sheep, pigs, cats, and dogs1. It is a combination of pyrantel and pamoic acid. It is used to study mechanisms underlying gut dysfunction in a murine model2. It has been used as an anthelmintic treatment of children in Bangladesh and has been studied for it′s effect on host physiology, growth, and biochemical status3.
Pyrantel pamoate is a nematode muscle cell-associated nicotinic agonist for the acetylcholine (ACh) receptor. Cholinesterase inhibitor.
1. The Impact of Concurrent and Treated Ancylostoma ceylanicum Hookworm Infections on the Immunogenicity of a Recombinant Hookworm Vaccine in Hamsters Kashinath Ghosh, Wenhui Wu, et al. J. Infect. Dis. 193, 155-162, (2006)
2. Mechanisms underlying gut dysfunction in a murine model of chronic parasitic infection Yasuaki Motomura, Waliul I. Khan, et al. Am. J. Physiol. Gastrointest. Liver Physiol. 299, G1354-G1360, (2010)
3. Anthelmintic treatment of rural Bangladeshi children: effect on host physiology, growth, and biochemical status Christine A Northrop-Clewes, Emily K Rousham et al Am. J. Clin. Nutr. 73, 53-60, (2001)
Activity of oxantel pamoate monotherapy and combination chemotherapy against Trichuris muris and hookworms: revival of an old drug. Keiser J, Tritten L, Silbereisen A, et al. PLoS Negl. Trop. Dis. 7(3), e2119, (2013)
Prevalence of the intestinal flukes Haplorchis taichui and H. yokogawai in a mountainous area of Phongsaly Province, Lao PDR. Chai JY, Yong TS, Eom KS, et al. Korean J. Parasitol. 48(4), 339-42, (2010)
Field effectiveness of pyrantel and failure of Parascaris equorum egg count reduction following ivermectin treatment in Italian horse farms. Veronesi F, Moretta I, Moretti A, et al. Vet. Parasitol. 161(1-2), 138-41, (2009)
Efficacy of Drontal Flavour Plus (50 mg praziquantel, 144 mg pyrantel embonate, 150 mg febantel per tablet) against Giardia sp in naturally infected dogs. Montoya A, Dado D, Mateo M, et al. Parasitol. Res. 103(5), 1141-4, (2008)
Lagochilascaris minor Leiper, 1909 (Nematoda: Ascarididae) in Mexico: three clinical cases from the Peninsula of Yucatan. Barrera-Pérez M, Manrique-Saide P, Reyes-Novelo E, et al. Rev. Inst. Med. Trop. Sao Paulo 54(6), 315-7, (2012)
Further evaluation in field tests of the activity of three anthelmintics (fenbendazole, oxibendazole, and pyrantel pamoate) against the ascarid Parascaris equorum in horse foals on eight farms in Central Kentucky (2009-2010). Lyons ET, Tolliver SC, Kuzmina TA, et al. Parasitol. Res. 109(4), 1193-7, (2011)
[A case of ascariasis in the gallbladder successfully treated with an anthelmintic injection into the gallbladder via a percutaneous transhepatic catheter]. Ikuta S, Mizuguchi Y, Tsuji Y, et al. Nihon Shokakibyo Gakkai Zasshi 107(5), 768-74, (2010)
Efficacy of pyrantel pamoate and ivermectin paste formulations against naturally acquired Oxyuris equi infections in horses. Reinemeyer CR, Prado JC, Nichols EC, et al. Vet. Parasitol. 171(1-2), 106-10, (2010)
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