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  • P6614 - Anti-phospho-Pyk2 (pTyr402) antibody produced in rabbit

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P6614 Sigma

Anti-phospho-Pyk2 (pTyr402) antibody produced in rabbit

affinity isolated antibody, buffered aqueous glycerol solution

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology, Antibodies to Phosphoproteins at Phosphotyrosine (pTyr),
species reactivity   chicken, human, rat
application(s)   western blot: 1:1,000 using chick embryo fibroblasts (CEF) cells expressing human Pyk2
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous glycerol solution
mol wt   antigen mol wt ~116 kDa
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... PTK2B(2185)
rat ... Ptk2b(50646)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

synthetic phosphopeptide derived from the region of Pyk 2 that contains tyrosine 402.

General description

Pyk2 (proline-rich kinase 2) is a protein that belongs to Tyr protein kinase family and is expressed in mesenchymal cells, epithelial cells, endothelial cells, neonatal cardiomyocytes, osteoclasts and neuronal cells. It has a crucial role in T and B cell antigen receptor signaling, cell cycle progression, metastasis, and NK cytotoxicity. It also modulates ion channel function and neuronal short- and long- term responses. Anti-phospho-Pyk2 (pTyr402) antibody can be used in western blotting (1:1,000). Rabbit anti-phospho-Pyk2 (pTyr402) antibody reacts specifically with Pyk2 (pTyr402) (116 kD approx.) of rat, chicken and human.

Physical form

solution in Dulbecco′s phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, containing 50% glycerol, 1.0 mg/ml BSA (IgG and protease free) and 0.05% sodium azide.

Application

Anti-phospho-Pyk2 (pTyr402) antibody can be used in immunoblotting (diluted 1: 1000).

Packaging

One vial is sufficient for 10 immunoblots.

Price and Availability


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WGK Germany  1
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