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P6972 Sigma

Monoclonal Anti-Interferon-γ−R-Phycoerythrin antibody produced in mouse

clone 25723, purified immunoglobulin, saline solution

Synonym: Monoclonal Anti-Interferon-γ

Properties

Related Categories Alphabetical Index, Analytical Cytology, Antibodies, Antibodies for Intracellular Cytokine Staining, Cell Biology,
species reactivity   human
application(s)   flow cytometry: suitable
clone   25723, monoclonal
antibody form   purified immunoglobulin
form   saline solution
isotype   IgG2b
shipped in   wet ice
storage temp.   2-8°C
Gene Information   human ... IFNG(3458)
biological source   mouse
conjugate   phycoerythrin (R-PE) conjugate

Description

Immunogen

recombinant human IFN-γ

General description

Human Interferon-γ (IFN-γ) is a Type I cytokine produced by the lymphocytes activated in response to specific antigens or mitogens. It has a pivotal role in activating primed macrophages for nonspecific tumoricidal activity as well as can stimulate monocytes for enhanced cytotoxicity against tumor cells. It also has several biological functions like inhibition of cell or tumor growth, promotion of B cell differentiation into plasma cells and antiviral activity. Further, it can enhance the cytotoxicity of natural killer cells and T-cells. Monoclonal anti-Interferon-γ−R-Phycoerythrin antibody reacts specifically with human IFN-γ.

Physical form

Solution in saline containing up to 0.5% bovine serum albumin and 0.1% sodium azide as a preservative.

Specificity

The conjugates will identify and quantitate cells containing intracellular forms of human IFN-γ by flow cytometry.

Preparation Note

Purified antibody is conjugated to R-phycoerythrin (PE).

Application

Monoclonal anti-Interferon-γ−R-Phycoerythrin antibody can be used in flow cytometry for detecting intracytoplasmic cytokines and enumerating cytokine-producing cells in a mixed population.

Price and Availability

Technical Service:

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